Phase 1
UC Davis Dietary Biomarker Development Center
The purpose of DBDC research at the University of California, Davis is to find a set of markers in the blood and/or urine that can be linked to consumption of specific fruits and vegetables. This will allow for better understanding of the link between diet and health-related outcomes. The results of this study will lead to the development of new methods to evaluate the nutritional status of individuals in both community and clinical settings. Food frequency questionnaires and diaries/recalls can be affected by intentional or unintentional misreporting, and thus can create errors in determining nutritional status. This study will lead to the development of an objective way to assess the consumption of specific fruits and vegetables by the general population.
Status:
Recruiting
Dietary Biomarker Intervention Core
This study at the Harvard School of Public Health will identify objective biomarkers of dietary intake that can serve as independent markers of dietary intake and complement current dietary intake assessment methods. The knowledge gained in this approach will thus address a critical gap with immediate benefits to the larger nutrition research community, both in observational and clinical trial settings, to improve the validity of major public health research initiatives. The Intervention Core will perform tightly controlled pharmacokinetic (PK) and dose-response (DR) feeding studies across a range of food items and food groups in diverse populations. The investigators will focus on common foods from the protein, carbohydrates, and dairy food groups: (1) chicken, beef, salmon, and soybeans; (2) yogurt, cheese; and (3) whole wheat bread, potatoes, corn, and oats.
Status:
Recruiting
Learn more on ClinicalTrials.gov
Phase 1 Seattle Dietary Biomarker Development Center
The Seattle Dietary Biomarker Development Center (S-DBDC) at the Fred Hutchinson Cancer Research Center aims to advance the science of measuring dietary intake by identification and validation of dietary biomarkers that improve upon self-reported diet. To accomplish this mission, the Seattle DBDC will carry out controlled feeding studies in healthy human volunteers. Metabolomics assays will be conducted on blood and urine specimens collected during the feeding studies for biomarker identification.
Status:
Recruiting
Learn more on ClinicalTrials.gov